VectorCHO Feed Medium is a versatile cell culture feed designed for use with multiple base media in fed-batch cultivation of Chinese Hamster Ovary (CHO) cells. This flexible feed medium is engineered to enhance cell productivity and recombinant protein yields across various CHO cell lines and production processes.
VectorCHO Feed is a chemically defined feed medium formulated for high-density fed-batch processes across multiple Chinese hamster ovary (CHO) cell subtypes. It is hydrolysate-free, animal-origin free (AOF), and does not contain L-glutamine. It contains 77 g/L D-glucose.
Recommended cell subtypes: CHO-DXB11, CHO DG44.
Recommended companion media: AltairCHO™, VegaCHO™ and CDFS36™ Feed Supplement.
This product is intended for research use or further manufacturing, including large-scale biopharmaceutical production. It is not intended for direct human administration or use as a drug substance or drug product.
Key features:
1) Versatile formulation compatible with most CHO base media;
2) Optimized nutrient composition for broad CHO cell line compatibility;
3) Supports both growth and production phase feeding strategies;
4) Enhances cell viability and reduces apoptosis in late-stage culture;
5) Consistent performance across different bioreactor scales;
6) Delivers high yields across different CHO cell lines while maintaining high cell densities and viability for robust bioprocessing;
7) GMP-ready for seamless R&D-to-GMP transition;
8) Robust intra- and inter-lot consistency (RSD <5%);
9) Flexible packaging formats (dry powder media or liquid).
VectorCHO Feed, used in combination with VegaCHO Medium and CDFS36 Feed Supplement, outperformed a competitor in CHO DG44 mAb expression, showing >500% titer increase on Day 14, with higher late-stage VCDs and viability.
VectorCHO Feed Medium is an excellent choice for biopharmaceutical manufacturers with diverse product portfolios and varying process requirements, providing flexibility and reliability in fed-batch processes.
