VegaCHO Medium is a premium serum-free cell culture medium specifically formulated for the cultivation of Chinese Hamster Ovary (CHO) cells. This medium is designed to deliver exceptional performance in terms of cell growth, viability, and recombinant protein production, making it suitable for demanding biopharmaceutical applications.
VegaCHO is a chemically defined basal medium formulated for thawing, passaging, and supporting high-density fed-batch processes across multiple Chinese hamster ovary (CHO) cell subtypes. It is hydrolysate-free, animal-origin free (AOF), and does not contain L-glutamine. It contains 6 g/L D-glucose.
Recommended cell subtypes: CHO DG44, etc.
Recommended companion media: HelixCHO™ Feed, VectorCHO™ Feed, and CDFS36™ Feed Supplement.
This product is intended for research use or further manufacturing, including large-scale biopharmaceutical production. It is not intended for direct human administration or use as a drug substance or drug product.
Key features:
1) Serum-free and animal-derived component-free formulation;
2) Optimized nutrient composition for maximum protein expression;
3) Excellent batch-to-batch consistency ensuring process reliability;
4) Supports extended culture periods with maintained cell health;
5) Compatible with all major CHO cell lines and production processes;
6) Delivers high yields across different CHO cell lines while maintaining high cell densities and viability for robust bioprocessing;
7) GMP-ready for seamless R&D-to-GMP transition;
8) Robust intra- and inter-lot consistency (RSD <5%);
9) Flexible packaging formats (dry powder media or liquid).
VegaCHO Medium, when fed VectorCHO Feed and CDFS36 Feed Supplement, outperformed a competitor in CHO DG44 mAb expression, showing >500% titer increase on day 14, with higher late-stage VCDs and viability.
VegaCHO Medium is recommended for use in research, process development, and commercial manufacturing of therapeutic proteins, providing a reliable platform for biopharmaceutical production.
